The Powder Vial Filling Machine is designed for accurate dosing of sterile powder into glass vials in pharmaceutical injection production. At the core of the machine, a servo-driven auger dosing system with interchangeable dosing wheels keeps fill weight stable from the first vial to the last. Dosing wheels are selected to match your powder’s flowability and bulk density, so the machine adapts to how your product actually behaves instead of forcing one setting across all formulations.

With 2 to 20 filling heads and a filling range of 0.5 to 100 ml, the machine can be configured to match different output targets and vial presentations. Dust extraction around the filling zone keeps powder inside the machine and protects the cleanroom environment, while the vial mouth area stays clean before stoppering.

The machine is designed in accordance with GMP requirements, with 316L stainless steel product contact parts and a 304 stainless steel frame. It connects directly with the tunnel sterilization oven upstream and the stoppering and capping machine downstream, and documentation is available to support your IQ, OQ, and PQ validation process.

Powder vial glass bottle

1. Vial Infeed from the Tunnel
Sterilized and depyrogenated vials arrive from the tunnel sterilization oven and are transferred onto the machine conveyor, entering the dosing zone in a continuous flow without manual handling.

2. Vial Positioning & Detection
The conveying system positions each vial precisely under the dosing wheel, and sensors confirm vial presence at every station — no vial, no dosing, keeping the powder inside the filling zone and avoiding waste.

3. Auger Dosing
The servo-driven auger dosing system rotates the dosing wheel to dispense an accurate powder charge into each vial, keeping fill weight stable from the first vial to the last. Dosing wheels are selected to match your powder’s flowability and bulk density.

4. Dust Extraction
Dust generated during dosing is drawn away by the extraction system around the filling zone, so powder stays inside the machine and the vial mouth area stays clean before stoppering.

5. Discharge to Stoppering & Capping
Filled vials are conveyed out of the dosing zone directly into the stoppering and capping machine, continuing the washing-sterilizing-filling-capping sequence without exposure to the environment.