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Serum Filling Machine

Automatic Blood Serum Liquid De-capping Filling Capping Machine
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Product Full Detail

Automatic Blood Serum Liquid De-capping Filling Capping Machine Our Automatic Serum Liquid Filling Machine is engineered to ensure maximum efficiency and hygiene during the filling and capping process. It incorporates a range of advanced technologies, from servo-driven bottle separation and positioning to an aseptic environment for the sterile transport of bottles. This cutting-edge machine offers unparalleled precision, making it an ideal choice for pharmaceutical companies, healthcare providers, and laboratories dealing with the packaging of sensitive liquids like blood serum.

Video

APPLICATION

Blood Serum Bottle

1. Bottle Feeding & Positioning
Empty pre-capped serum bottles are fed onto the conveyor and separated by the servo-driven feeding system, which positions each bottle accurately for the stations ahead.

2. Cap Loosening & Lifting (De-capping)
At the de-capping station, a servo motor loosens the screw cap and lifts it slightly, keeping the cap attached to the bottle. The bottle opening is exposed for the shortest time possible, and the inner cap surface is never touched by hand.

3. Precision Filling
The peristaltic filling head descends into the bottle to about two-thirds of its depth and dispenses the serum in a two-stage fill along the inner wall, preventing foaming and splashing. The product only touches the 316L-compatible tubing, keeping the product path hygienic.

4. Level Verification
A liquid level detection system checks each bottle after filling, confirming the correct volume and preventing overfilled or underfilled bottles from moving forward.

5. Re-capping & Torque Tightening
The capping head returns to its position, picks up the lifted cap, and tightens it to a controlled torque using the electronic friction plate. Caps are sealed consistently without over-tightening or damage to the outer cap wall.

6. Discharge & Line Transfer
Finished bottles are released to the outfeed conveyor and transferred to the labeling machine and carton packing machine, completing an automated serum packaging line.

TECHNICAL SPECIFICATION

ModelHBSF-4
Suitable ProductsBlood serum, sterile liquid preparations [To be confirmed]
Suitable Bottle Type20-500ml
Filling Volume20-500ml
Filling SystemPeristaltic pump, two-stage filling
Filling Accuracy99%
Working Speed10-50 BPM
De-capping MethodServo-driven cap loosening and lifting
Capping SystemElectronic friction plate, adjustable torque
Material Contact Parts316L Stainless Steel
Machine Body Material304 Stainless Steel

WHY CHOOSE US

🎯 End-to-End Machinery Solutions 

From concept to commissioning, We handle everything Whether you need injectable filling lines, solid dosage packaging, or topical product systems, we deliver complete turnkey solutions tailored to your production requirements.
✓ Injectable filling systems (vials, syringes)
✓ Filling products material (liquid, powder, creams, ointments, gels)
✓ Custom integration with existing lines

📋 Comprehensive Compliance Support

We don't just deliver machines—we ensure they meet global regulatory standards. Our team handles all documentation, testing, and validation to get you production-ready faster.
✓ Full validation packages (IQ/OQ/PQ)
✓ Factory Acceptance Testing (FAT) & Site Acceptance Testing (SAT)
✓ Operator training & SOP development
✓ Regulatory file support (GMP, cGMP)

🔧Lifetime After-Sales Support

Your success is our long-term commitment Our relationship doesn't end at installation. We provide ongoing maintenance, upgrades, and spare parts management to maximize your equipment uptime and ROI.
✓ 24/7 technical support hotline
✓ Preventive maintenance programs
✓ Equipment upgrade consultancy
✓ Genuine spare parts with fast delivery
Your Journey to the Perfect Filling Solution

Why Choose Us

🎯 Complete Turnkey Solutions
From design to installation, we handle every step of your production line setup

🏭 ISO-Certified Factory
Own manufacturing facility with strict quality control and proven production capacity

🎨 Flexible Customization
Tailor-made solutions that integrate seamlessly with your existing production lines

📋 Full Compliance Support
Complete validation packages (IQ/OQ/PQ), FAT/SAT, and regulatory documentation

🌍 Global Project Experience
500+ installations across 40+ countries with multilingual technical support

🔧 24/7 After-Sales Service
Preventive maintenance, spare parts management, and upgrade consultancy

Common Questions about Serum Filling Machine

What is a de-capping filling capping machine?
A de-capping filling capping machine is a specialized filling system for bottles that are supplied pre-capped, such as blood serum and sterile liquid bottles. Instead of removing the cap completely, the machine loosens and lifts the cap with a servo-driven head, fills the bottle, and then re-tightens the same cap, minimizing the time the bottle opening is exposed.
Why use de-capping instead of filling uncapped bottles?
For sterile products like blood serum, every extra second an open bottle spends outside a protected environment increases contamination risk. The de-capping process keeps the cap attached to the bottle throughout filling, so the bottle is never fully open, the inner cap surface is never handled, and the product path stays protected between the cap lifting and re-capping stations.
What products is this machine suitable for?
The machine is designed for blood serum and other sensitive sterile liquids in the pharmaceutical, medical, and healthcare fields, including serum bottles and similar small-dose liquid containers. It is suitable for products where gentle handling, accurate dosing, and contamination control are critical, such as clinical reagents and diagnostic kit liquids.
How does the machine prevent foaming and splashing during filling?
The filling head descends into the bottle to about two-thirds of its depth before dosing starts, and filling runs in two stages, so the liquid is dispensed gently along the bottle inner wall instead of dropping from above. Combined with peristaltic pump dosing, this prevents the foaming and splashing that high-speed surface filling would cause with protein-containing liquids like serum.
What materials is the machine made of?
The machine structure is made of 304 stainless steel, and all parts in direct contact with the product are 316L stainless steel, which resists corrosion and supports GMP-compliant cleaning. Filling is handled by peristaltic pumps, so the product only touches the pump tubing, keeping the product path hygienic and easy to maintain.
How does the capping system protect the bottle and cap?
The capping head uses an electronic friction plate instead of a traditional spring mechanism, so the capping torque is adjusted electronically and stays consistent without mechanical wear over time. The overload torque is adjustable for different bottle and cap types, and the design leaves the outer cap wall undamaged, keeping the finished package both sealed and clean-looking.
How does the machine prevent filling and capping errors?
The machine is equipped with no-bottle-no-filling and no-cap-no-capping detection, so stations stay idle when a bottle or cap is missing instead of dispensing product or crushing caps. A liquid level detection system additionally verifies that each bottle is filled to the correct level, preventing overfilling and underfilling from leaving the machine.
Can the machine be integrated into a full packaging line?
Yes. The machine uses frequency conversion speed control, so its operating speed can be adjusted continuously to match the rest of the line. It connects with labeling machines and carton packing machines downstream, forming an automated serum packaging line from filling to secondary packing with minimal manual handling.

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