
Vertical Rotary Ultrasonic Bottle Washing Machine
This machine is suitable for cleaning controlled or molded antibiotic bottles in pharmaceutical and health product factories. It can also be used for cleaning injection ampoules or oral liquid bottles. The machine has a vertical structure and uses a robotic arm to grip the bottle and a spray nozzle for reciprocating tracking. It utilizes ultrasonic cleaning and alternating water and air cleaning principles to clean the containers. It features a low bottle breakage rate, wide versatility, stable operation, and no cross-contamination of water and air pipelines, meeting GMP requirements.
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Product Full Detail
- Vertical Ultrasonic Vial Washing Machine mainly used to wash penicillin vials, oral liquid bottles and ampoules. The ultrasonic cavitation, circulation water, WFI and compressed air device are set apart.
- It is one of the main equipment for new GMP technology requirements. Can be used for single or in production line.
Feature
- Circulating water, WFI and compressed air can apply to spraying needles which have has obtained national patent, to prevent cross contamination, circulating water can recycle and filter separately, save the energy and cost.
- The cover can lift automatically, supply oil intensively, can relieve artificial work-load, decrease equipment fault rate, to make machine run steadily.
- Auto sampling, tail bottle emptying function.
- Equip with full digital differential pressure transmitter, monitor the water pressure, add ultrasonic intensity detector to make the whole washing process traceable, meet new GMP key parameter traceable demands.
- Non-metal components are processed with imported polyformaldehyde.
Video
APPLICATION
automated industrial cleaning system used primarily in pharmaceutical, biotech, and cosmetic manufacturing to sterilize and wash glass vials, ampoules, and small bottles.

How It Works
- Ultrasonic Pre-Washing: Bottles enter a water tank where high-frequency sound waves create microscopic bubbles that scrub away stubborn particles on both inner and outer surfaces without damaging the glass.
- Rotary Mechanical Gripping: A vertical rotating drum and robotic mechanical hands clamp, lift, and flip the bottles 180 degrees so the openings face downward.
- Alternating Jet Rinsing: Spray needles track and penetrate deep inside the inverted bottles, flushing them with alternating cycles of purified water, circulating water, Water for Injection (WFI), and compressed air/air drying.
Key Features
- Compact Vertical Design: Saves valuable cleanroom floor space while maintaining high output speeds.
- No Cross-Contamination: Independent fluid and air paths prevent mixing or contamination between utility water and sterile circuits.
- GMP Compliance: Built with corrosion-resistant 304/316 stainless steel and transparent enclosure guards.
TECHNICAL SPECIFICATION
| Model | HBWM-100 |
|---|---|
| Suitable Vial/Ampoule Volume | 2-5 ml |
| Processing Capacity | 200-220 vials/min |
| Water Consumption | Approx. 0.6 m³/h |
| Water Pressure | 0.15-0.18 MPa |
| Compressed Air Consumption | Approx. 45 m³/h |
| Compressed Air Pressure | 0.6-0.8 MPa |
| Power | 12.5 kW |
| Machine Weight | Approx. 2200 kg |
| Machine Dimensions | 2450*2250*1450 mm (L*W*H) |
WHY CHOOSE US

End-to-End Machinery Solutions
From concept to commissioning, We handle everything Whether you need injectable filling lines, solid dosage packaging, or topical product systems, we deliver complete turnkey solutions tailored to your production requirements.
✓ Injectable filling systems (vials, syringes)
✓ Filling products material (liquid, powder, creams, ointments, gels)
✓ Custom integration with existing lines
✓ Injectable filling systems (vials, syringes)
✓ Filling products material (liquid, powder, creams, ointments, gels)
✓ Custom integration with existing lines

📋 Comprehensive Compliance Support
We don't just deliver machines—we ensure they meet global regulatory standards. Our team handles all documentation, testing, and validation to get you production-ready faster.
✓ Full validation packages (IQ/OQ/PQ)
✓ Factory Acceptance Testing (FAT) & Site Acceptance Testing (SAT)
✓ Operator training & SOP development
✓ Regulatory file support (GMP, cGMP)
✓ Full validation packages (IQ/OQ/PQ)
✓ Factory Acceptance Testing (FAT) & Site Acceptance Testing (SAT)
✓ Operator training & SOP development
✓ Regulatory file support (GMP, cGMP)

🔧Lifetime After-Sales Support
Your success is our long-term commitment Our relationship doesn't end at installation. We provide ongoing maintenance, upgrades, and spare parts management to maximize your equipment uptime and ROI.
✓ 24/7 technical support hotline
✓ Preventive maintenance programs
✓ Equipment upgrade consultancy
✓ Genuine spare parts with fast delivery
✓ 24/7 technical support hotline
✓ Preventive maintenance programs
✓ Equipment upgrade consultancy
✓ Genuine spare parts with fast delivery
Your Journey to the Perfect Filling Solution
Why Choose Us
🎯 Complete Turnkey Solutions
From design to installation, we handle every step of your production line setup
🏭 ISO-Certified Factory
Own manufacturing facility with strict quality control and proven production capacity
🎨 Flexible Customization
Tailor-made solutions that integrate seamlessly with your existing production lines
📋 Full Compliance Support
Complete validation packages (IQ/OQ/PQ), FAT/SAT, and regulatory documentation
🌍 Global Project Experience
500+ installations across 40+ countries with multilingual technical support
🔧 24/7 After-Sales Service
Preventive maintenance, spare parts management, and upgrade consultancy
From design to installation, we handle every step of your production line setup
🏭 ISO-Certified Factory
Own manufacturing facility with strict quality control and proven production capacity
🎨 Flexible Customization
Tailor-made solutions that integrate seamlessly with your existing production lines
📋 Full Compliance Support
Complete validation packages (IQ/OQ/PQ), FAT/SAT, and regulatory documentation
🌍 Global Project Experience
500+ installations across 40+ countries with multilingual technical support
🔧 24/7 After-Sales Service
Preventive maintenance, spare parts management, and upgrade consultancy
Common Questions about Vertical Rotary Ultrasonic Bottle Washing Machine
What is a vertical ultrasonic vial washing machine?
A vertical ultrasonic vial washing machine is a pharmaceutical washing machine that cleans vials, ampoules, and oral liquid bottles using ultrasonic coarse washing followed by alternating water and compressed air fine washing. Bottles are clamped by mechanical hands and inverted 180 degrees during the process, so both the interior and exterior of each bottle are thoroughly cleaned before sterilization and filling.
How does the machine wash the bottles?
The washing process runs in two stages. First, bottles are coarsely washed in the ultrasonic tank, where cavitation removes particles bonded to the glass surfaces. Then mechanical hands rotate each bottle 180 degrees, and washing needles flush the interior with water and compressed air alternately in multiple cycles before the bottle is rotated back and discharged. Water and air pipes are kept separate throughout to avoid cross contamination.
What bottles is the machine suitable for?
The machine is designed for small-volume injectable containers, including 2-5 ml vials and ampoules as well as oral liquid bottles with diameters of approximately 10-30 mm. The vertical rotary drum design keeps the bottle breakage rate low, and change parts are easy to replace when switching between bottle specifications.
What water quality does the machine require?
The fine washing stage uses purified water or Water for Injection (WFI), passed through 0.2 μm and 0.45 μm filters before reaching the washing needles. Circulating water can be recycled and filtered separately to reduce water consumption and operating cost. Water and compressed air pressures are monitored continuously, with automatic low-pressure alarms to protect washing quality.
How does the machine support GMP documentation and traceability?
The washing process is monitored by digital differential pressure transmitters and ultrasonic intensity detection, making key washing parameters traceable throughout production. The machine can be equipped with a data recording and storage management system designed to support electronic record requirements such as 21 CFR Part 11. This gives your quality team verifiable washing records for each batch.
What is the production capacity?
The machine reaches a processing capacity of 200 to 220 vials per minute for 2-5 ml bottles. This output matches the speed range of upstream bottle washing line requirements and downstream tunnel sterilization and filling equipment, and the conveying speed is matched to your line during commissioning.
Does washing also sterilize the bottles?
No. Washing removes particles, residues, and contaminants but is not a sterilization step. Washed bottles should pass through a tunnel sterilization oven for dry heat sterilization and depyrogenation before entering the aseptic filling area, completing the washing-sterilizing-filling sequence required for injectable production.
How does the design prevent cross contamination and microbial growth?
The coarse washing and fine washing areas are separated, circulating water, WFI, and compressed air each flow through independent needles and pipelines, and transmission components are isolated from the cleaning medium and bottles. An optional compressed air evacuation system can blow residual water out of the pump, filter housing, and pipelines after production stops, preventing microbial growth in standing water.
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